Typically, most sellers will expect buyers to come to their area. Sometimes sellers have their preferred meet-up locations already in mind and will let the buyer know when & where they can meet.
Always be sure to meet in a public location, such as your local coffee shop or library, and always during normal business hours. Many Police Departments around the country are now offering Safe Deal Zones in front of their Police Stations, often with security cameras for added peace-of-mind.
Avoid giving strangers your address and never invite a stranger into your home.